The manuscript highlights how DDSsincluding stimuli-responsive nanoparticles, targeted ligands, and biodegradable carriersenhance solubility, bioavailability, and tissue-specific delivery of urate-lowering agents (e.g., allopurinol and febuxostat) and anti-inflammatory therapies (e.g., colchicine and IL-1 inhibitors) (Chen Z
[2] Maternal deficiency increases the risk of miscarriage, neural tube defects, and delayed development in offspring
Human evidence is now beginning to follow
Vitamin D deficiency and the COVID-19 pandemic
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